Could 200Mg Of Thaimin Taken Regularly...

[sandyRoe]

...have any effect on mood, particularly anxiety?

[pastafreak]

That's one of the B vitamins isn't it. I believe all the B vits are known to help the nervous system, and in turn anxiety. B6 and B12 are particularly helpful.

[sandyRoe]

Yes, it's B1.

[pastafreak]

I just googled it. Do you take it now...as I know you've mentioned having some issues with drinking. B1 is used in treatment from what I just quickly read.
When I was having a recurrence of anxiety a few months ago, it was B6 and 12 that came up as most useful...and I've taken them both seperately and in a B complex in the past.
Right now I'm taking B12.

https://www.healthline.com/health-news/vitamin-b6-supplements-may-help-reduce-anxiety-depression#:~:text=Researchers%20say%20high%20daily%20doses,potatoes%2C%20spinach%2C%20and%20bananas.

https://www.mayoclinic.org/diseases-conditions/depression/expert-answers/vitamin-b12-and-depression/faq-20058077

[sandyRoe]

I started a few days ago. They were prescribed by my GP.
I am feeling a bit better but that might just be something of a placebo effect or the knowledge that I've set change in progress.

[Sqad]

My feelings on the subject:

There is no good medical studies that show that high levels of VitB have any effect on mood if your blood levels of Vit B complex is normal.

I have little faith in the treatment of depression or anxiety states with B complex.

if one does have low B complex Vitamins in the blood and one is suffering anxiety and/or depression, then one cannot assume a causal link.

All my above comments exclude VitB12 deficiency which is quite a different problem.

[sandyRoe]

I've read prolonged heavy drinking can deplete Vitamin B, sometimes even leading to Beriberi. Hopefully, I'm nowhere near that yet.

[sandyRoe]

I'll continue taking the tablets. Even if they do no good they'll probably do no harm.
Thank you both.

[pastafreak]

A study from earlier this year...

https://pubmed.ncbi.nlm.nih.gov/35851507/

[Sqad]

pasta

////Conclusions: Our results suggest that high-dose Vitamin B6 supplementation increases inhibitory GABAergic neural influences, which is consistent with its known role in the synthesis of GABA.////

I really have no idea what the above means taken from your "link

////"Vitamin B6 supplementation reduced self-reported anxiety and induced a trend towards reduced depression, as well as increased surround suppression of visual contrast detection, but did not reliably influence the other outcome measures. Vitamin B12 supplementation produced trends towards changes in anxiety and visual processing.////

Also I have no idea what the above means particularly when quoted " but did not reliably influence the other outcome measures."

Lets's hope the prof will see this and enlighten me.

[Sqad]

Pasta ....your link was invloved in the study of just two B vitamins B6 and B12.

The OPer is enquiring about B1 .........which is not involved in your link.

[chamois]

Sqad, just found the full version of the paper mentioned by pasta on an university archive website as a downloadsble pdf. The first few paragraphs of the page are a bit messy but the full article is readable a little further down. I'll never regard marmite the same way again!


https://centaur.reading.ac.uk/106316/1/Human%20Psychopharmacology%20-%202022%20-%20Field%20-%20High%E2%80%90dose%20Vitamin%20B6%20supplementation%20reduces%20anxiety%20and%20strengthens%20visual.pdf

[chamois]

Sorry, you need to click on the "Text Open Access" link just below the title to the right of the small box. It'll then download the pdf.

[pastafreak]

I probably should have linked to one of the articles written in layman's terms.
I felt that as Sandy was seeking help for anxiety, that mentioning the possible benefits of other B vitamins might be useful to him.

[Sqad]

Thanks pasta, but as I mentioned that trial invlved two of the B complex of vitamins, B12 and B6, sandy's enquiry is about B1 (thiamine).

[Sqad]

pasta, you have great support as the supplement industry in the UK is worth well over a billion pounds.