Leg the alternatives to animal tsting for cosmetics, involve eyetex, a synthetic cornea that reacts the same way, corneas from eye banks that are no longer suitable for transplant. Computer testing. Volunteers from humans when the products are already together in a similar formula in an alternative product. Skintex, synthetic skin which can react to 5000 different chemicals. Epipack, human cloned skin. Ames test is enzyme based testing.
Rabbits are almost solely used for the eyetest and it is incredibly unreliable. A human eye is not the same.
With shampoos and the like, they feed the animal up to 50% of its weight with that product to see how much will kill it. They have to do this to 50 animals to see at which dose over half the animals dye. This is utterly unreliable, just look at medicine, morphine relaxes us but excites cats, aspirin poisons cats and penicillin kills a lot of animals.