People who think of Room 101 as a cheap TV programme and not the scariest place in the world (as George Orwell wrote it in 1984) - though I should really blame the TV executive that came up with the idea.
also JohnPPotts - I DO know the original meaning. but everyone knows what i meant by this question and it's a lot snappier than 'what stuff really really annoys you that you would like to see eradicated from exsistence?' ;)