Depends exactly what you mean by "run"?
"The Board of Directors" run the company so in effect, presuming they all are directors as you say, they all do.
You probably meant "control" which is a different thing. No individual "controls" the company and if it can be presumed that husband and wife will back one another there is a deadlock position if they vote differently to the other shareholder at General Meetings of the company. Which would mean no proposal would succeed so status quo would remain if the shareholders couldn't agree.
That has nothing to do with board meetings though. The actual capital held has got nothing much to do with procedures at board meetings. If all three are directors then it's likely that any two could vote something through without agreement of the third. Would depend what, if anything, the company has published as guidelines for procedures at board meetings.