As a culture, we are appearence-obsessed, and never more than with people in the public eye.
There are swathes of magazines whose raison d'etre is nothing else than to point and laugh at the imperfections of celebrities - and that itself is a reflection of how trivialised people's lives can be.
To address the Question, I don't think there is a woman or man with an IQ above room temperature who is not aware of their physical shortcomings on a daily basis.
It really doesn't need input from our nearest and dearest, and certainly not from complete strangers to emphasise that these defects, small and large, are noticeable.
What it does need is for us to learn to celebrate our uniqueness, and try to avoid judging others by some stereotypical image that we can't all manage.
I am someone who has not been sprayed with evolution's expensive cologne, but I am aware of my good points, and rejoice in them, and make the best of the rest.