I would imagine it has more to do with the discovery of America itself, Dot. One of the principal elements of the renaissance was the rediscovery by Europe of Greek mathematics through contact with Muslim Spain. Granada was a Spanish tribute state for over 200 years before its surrender in 1492. This led directly to the advances in navigation which allowed Columbus (among others) to establish the sea routes necessary for discovery and colonisation. Spain and Portugal were the principal beneficiaries of this new science establishing colonies (and a large new income stream) from South, Central and finally North America (Mexico, Florida, California and Texas). The Elizabethan impact was pretty small to start with, largely confined to piracy on the Iberians. In the course of the Spanish incursions three major civilizations pretty much ceased to be, Inca, Aztec and finally Maya. The European influx was technologically superior; the wheel, the horse, gunpowder, steel, but the twin colonialist aims, a need for economic wealth and power and the desire to spread Christianity probably were the two things that long-term spelled an end to indigenous cultures.