I always told my children the same story about drugs - the difference with legal and illegal drugs is very simple -
if you buy a pack of Paracetamol in Edinburgh one day, and Torquay the next, you will get the same product because it is manufactured under licence.
If you buy heroin from the same locations, you have no idea what you will get, because drug dealers will vary quantities and strengths, to say nothing of diluting with chalk dust, rat poison, flour, etc. etc.
That is why heroin addicts overdose - they have no idea of the strength of the drug from one pack to the next, and overdosing is as simple as that.
It's a great leveller, from the street corner junkie to the famous wealthy actor - and the tragedy is the same anywhere, any time - a life is lost to addicition, and that is really sad, regardless of talent, or perceived loss to the arts, another sad individual with demons they can't deal with, has felt their demons deal with them.