I think this may be a misquote or mishearing of "He's been on my t*ts" as in "such and such really gets on my.... personally I prefer "that really frosts my underwear"
In The Merchant of Venice, Shylock says "Now I have thee on the hip" It's not a phrase that I've heard outside the play, but it seems to mean "i've got your bang to rights" (or the Elizabethan equivalent).
Shylocks speech I think is a wrestling term. When you get your opponent on your hip, it means that you can throw them on the floor and they can't stop you