Ok ... This Goes Back To Saturday . . .

[Cryptomaniac]

. . but what a stinker, albeit with some memorable clues. One to go: 22ac He directs agents to lose (6). Solution must be MISLAY (M + ISLAY, a scottish island which is part of the puzzle's theme). Can I take it that M is the director of spies of James Bond fame, more recently resurrected as a she in the form of Judi Dench ... but then rudely despatched in Skyfall?
And if 27 ac is SPELLBIND - Take turns to restrict entrance (9) - isn't it a bit unfair, grammatically, to have spell = turns?

[frugalfred]

I agree with mislay.
"spell" - one's turn at work?
Poor clue though.

[Lie-in King]

Mislay - yes, as you describe

Spellbind - http://www.thefreedictionary.com/spell

^ spell (3) v.intr.

[Cryptomaniac]

Thanks to Frugalfred and Lie-in King. Yes, I agree that spell and turn are close enough in meaning for one of the definitions of spell, but surely 'turns' in the clue should be singular?

[chelle7272]

To spell is also to take turns with someone,
verb (used with object)
8.
to take the place of for a time; relieve: Let me spell you at the wheel.

[Cryptomaniac]

Thanks Chelle. Yes, I'd never heard 'spell' in that sense used as a verb.