The prospect of jail may make iiars of us all. One person, Guede, is serving time for the murder, so it's not quite right to say, satiricallly, that nobody killed her. Knox had a goodish run for a reasonable doubt, so it is understandable that she would fight it; who wouldn't ? And if she, or anyone, wants to fight, it is not the lawyers' fault. Would you tell a client to plead guilty and face life in jail, if they persisted in denying the charge? You never know; they might be innocent. or not provenly guilty, and it's not the lawyer's job to act as judge and jury. You can point out the defects in the defence case put forward, and see what the client says, always remembering that some people aren't guilty but prefer a lying defence to the true one, simply because they don't think, in their ignorance, that the true one is a defence or because they think the lying one sounds better.