1. Plug in the USB Card Reader
2. On your keyboard hold down the Windows key, between Ctrl and Alt, and press the "Pause/Break" button next to Scroll Lock in the top right-hand corner of the keyboard. This will show the System Properties dialog.
3. Under the Hardware tab, press the Device Manager button. This shows a list of all hardware on your PC. If any of those items are expanded and there's a yellow circle with an exclamation mark it means that there's a hardware issue with that device. If the card reader has a yellow exclamation over it, right click in the item and press "Uninstall". This will uninstall the faulty driver. DO NOT uninstall anything unless you're absolutely sure that its the card reader as it could cause that device to stop functioning properly.
4. Restart your machine.
5. When you reload, you'll get an "New Hardware Found" wizard. Just pop your driver CD you got with the card reader into the CD Drive and let Windows install the device. Although it probably makes no difference, I always prefer letting windows install my devices than the software that comes with the unit.
You should now be up and running on the Windows side of things. If this doesn't work, it could be the device itself that's faulty. Also, be warned, uninstalling drivers in Device Manager can be dangerous if you're not careful. Uninstalling anything with a yellow exclamation is usually OK, because the exclamation means the device has a problem and isn't functioning, so uninstalling it won't make a difference to the computers functions.