the dc10's persistent early issue was the locking mechanism of the cargo door. after AA96 lost its door at Windsor Ontario a solution was designed but because there was no airworthiness directive it wasn't mandated. The result was the loss of Turkish 981 at Ermenonville in 1974.
AA191 lost an engine at Chicago in 1979 as a result of a flawed maintenance regime, the plane was a hull loss because the left wing slats lost control pressure, retracted and stalled the wing.
United 232 suffered an uncontained fan disk failure, but again the crash at Sioux City was due to an almost total loss of control pressure.
of a total fleet size of 446, there were 32 hull loss incidents and just over 1200 occupant fatalities, which compares favourably with other craft of the same era.