ive been on them about 3 months, it says they take 2 to 4 weeks to take effect, and with me it took the full month before they started to make me feel better, I thought they were never going to work. Im on the lowest 10mg, and the only side effect ive had is a very dry mouth and metalic taste, It says it causes sleep disturbence, but that was a problem I have anyway. Other than that I havent had any other side effects. They have taken the edge off my anxiety, my probems are still ongoing, but im coping better, and I do feel better for taking them.