Except in the highly unlikely event that Theresa May judges political suicide to be preferable to carrying out Brexit it's clearly going to happen now. It bothers me, and should bother everyone else, that we still don't have a clue what her intentions are yet. I'm cautiously optimistic that May having been a (closet) Remainiac means that her version of Brexit will end up being largely similar to my hopes, but then again I don't think that most Brexiters would be happy with the way I'd like things to be. More likely the deal we get will be the sort of compromise that ends up pissing everybody off and satisfying nobody in particular apart from big business.
But anyway. It stands to reason that, whatever Brexit now is, we had better make it work. I do believe that to be possible -- I even said so before the referendum. I also would have thought that it's possible in more than one way.
Whatever Brexit leads to, though, we'll still want to be an attractive place to set up business. As far as I can see, that means *not* taking the "well sod you then" attitude to any business that's worried about the UK leaving the single market, or some such. Even if Togo's right and new businesses would take their place, this would only leave us in the same position as before and not improve anything. Being friendly to the EU and opening trade to the wider world shouldn't be mutually exclusive options.