Yes. A few ways. First, just copy all your iTunes stuff across to your D drive, the folder my documents\my music\itunes
now in there you'll see an iTunes library file. You can delete that, and it'll forget where all your songs are. Then you can open iTunes again and goto edit->preferences->advanced, and change the iTunes folder to be the one on your D:. Then choose file->add to library, and choose all your songs again from the D drive. Other ways of going about it, but this is perhaps the easiest for the user.