Go to
http://cruiseforums.cruisecritic.com/index.php and sign up for free. On there you can go on the Ports of call board with any queries about the ports. You can also sign up to the roll call for your cruise to 'meet' others on your cruise. This can be very good, as Cruise Critic members often sort out better and cheaper excursions than the ones available through the cruise line. I can't recommend that you go to the site enough! Which ship are you going on? As to Bay of Biscay, like anywhere it just depends what the weather is like. I've been across the Bay twice with no rpoblems at all and last year went round the notorious Cape Horn in a flat calm! You just never know! as an example of advice you will get on the CC boards, you will dock in Civitivecchia for Rome. The cruise line will charge you £50+ for a round trip bus journey just to get you to Rome, whereas if you get the port bus to the dock gates, walk 400yds down the road to the station, you can get a return train to Rome for €9 and that includes the metro!